Diferencia entre revisiones de «Instituto Europeo de Bioinformática»

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El '''Instituto Europeo de Bioinformática''' ('''EBI''', por sus siglas en inglés) es una organización académica sin ánimo de lucro que forma parte del '''Laboratorio Europea de Biología Molecular'''. El EBI es una centro dedicado a la investigación y uso de servicios [[Bioinformática|bioinformáticos]]. Administra [[base de datos|bases de datos]] que contienen secuencias de [[ácido nucleico|ácidos nucleicos]], [[proteína]]s y estructuras macromoleculares.
== Grupos ==
; [http://www.ebi.ac.uk/msd/ Macromolecular Structure Database] (Kim Henrick)
: Proporciona lista de proteínas (estructura cuaternaria o [[macromolécula]]s) para cada entrada en la base de datos de proteinas (PDB)<!-----------
; [http://www.rcsb.org/pdb/]. It is also a member of the [[Worldwide Protein Data Bank]], and is of the three worldwide sites that accept, process and distribute macromolecular structure data.
; [http://www.ebi.ac.uk/panda PANDA Protein And Nucleotide DAtabase group][[Ensembl]] (Rolf Apweiler & [[Ewan Birney]])
: Provides, for almost 35 species, a [http://www.ensembl.org/ genome browser], public access to the [[MySQL]] databases of annotations shown in the browser, and a [[Perl]] [[API]] for accessing the database. The group is divided fairly equally between the EBI and the [[Wellcome Trust Sanger Institute]] with gene builders and web team on the Sanger side, and core database and [[comparative genomics]] teams at the EBI.
; [http://www.ebi.ac.uk/Thornton Thornton Group] ([[Janet Thornton]])
: Using biomolecular structures, tries to understand enzyme active sites, protein-protein interactions, protein-ligand interactions, protein-DNA interactions and structure and modelling.
; [http://www.ebi.ac.uk/Goldman Goldman Group] (Nick Goldman)
: Develops methods for the analysis of DNA and amino acid sequences to study evolution.
; [http://www.ebi.ac.uk/microarray/ Microarray Group] (Alvis Brazma)
: Uses microarray technology to analyse the sequence data from the genome projects to identify which genes are expressed in a particular cell type of an organism.
; [http://www.ebi.ac.uk/Rice/ Peter Rice Group] (Peter Rice)
: Investigates & advises on the [[e-Science]] and [[Grid computing|Grid]] technology requirements of the EMBL-EBI, through application development plus participation in standards development. See [[MyGrid]] and [[EMBOSS]]
; [http://www.ebi.ac.uk/compneur/ Computational Neurobiology Group] (Nicolas Le Novère)
: The interests of the group Computational Neurobiology revolve around [[signal transduction]] in [[neurons]], ranging from the [[molecular structure]] of [[membrane proteins]] involved in [[neurotransmission]] to modelling signalling pathways. A strong focus is the molecular and cellular basis of [[synaptic plasticity]] in neurons of the [[basal ganglia]]. The group also provide tools and resources for [[computational systems biology]], including the [[SBO]], the Systems Biology Ontology, [[MIRIAM]] Resources, plus software to develop models. A main project of the group is the [[BioModels Database]], which allows biologists to store, search and retrieve published mathematical models of biological interest.
; [http://www.ebi.ac.uk/Rebholz/ Rebholz Group] (Dietrich Rebholz-Schuhmann)
: Focuses on extraction of facts from scientific literature in molecular biology. The main methods are based on Finite State Automatons (FSAs). In the past has worked on the identification of protein-protein interactions, acronyms and descriptions of mutations.
; [http://www.ebi.ac.uk/huber/ Huber Group] (Wolfgang Huber)
: Focuses on gene transcription and protein-DNA binding analysis with DNA microarrays; statistical computing and high-throughput cellular assays and genetic interaction screens.
; [http://www.ebi.ac.uk/proteomics/ Proteomics Services Team] (Henning Hermjakob)
: Provides databases and tools for the deposition, distribution and analysis of proteomics and proteomics-related data.
; [http://www.ebi.ac.uk/interpro/ InterPro Group] (Sarah Hunter)
: Develops and maintains the InterPro project, an integrated documentation resource for protein families, domains and functional sites that is used for small and large-scale functional classification of proteins.
; [http://www.ebi.ac.uk/luscombe/ Regulation Group] (Nick Luscombe)
: Focuses on the genomic analysis of regulatory systems.
; [http://www.ebi.ac.uk/bertone/ Bertone Group] (Paul Bertone)
: Genomic analysis of developmental pathways, with a focus on differentiation and lineage commitment in mammalian embryonic stem cells.
; Database Application Group (Weimin Zhu)
: Consists of software engineers from the Sequence Database Group, and database professionals from the Database Support Team, which belongs to the EBI IT Service Group. It supports software and database development for new projects, and maintains support for the projects in production. It continually does research in software engineering and database technologies, to meet new requirements from users, and to find better solutions to the challenges in areas such as solid application framework, data integration and best practices.
; [http://www.ebi.ac.uk/literature/ Literature Services] (Peter Stoehr)
: This group is in charge of the development and maintenance of [http://www.ebi.ac.uk/citexplore CitExplore] and related services.
; Systems Group (Petteri Jokinen)
: Maintains and develops state-of-art computing infrastructure on which most EBI operations are run.
; [http://www.ebi.ac.uk/es/index.html External Services Group] (Rodrigo Lopez)
: Develops and maintains [http://www.ebi.ac.uk/tools/webservices/ Web Services APIs] for most tools available from EMBL-EBI, The [[EB-eye_EBI's_Search_Engine]], [http://srs.ebi.ac.uk/ EBI SRS servers], [http://www.ebi.ac.uk/2can/ 2can] for external as well as internal users. See also [http://www.ebi.ac.uk/es/ EBI External Services]
; Bioinformatics educational resource [http://www.ebi.ac.uk/2can 2can Bioinformatics]
: Provides short and concise introductions to basic concepts in molecular and cell biology and bioinformatics. It focuses on making it as easy for the user to understand which tools and databases are available from the EBI and collaborating sites. It also provides links to other sites where similar resources are maintained and well supported.
; [http://www.ebi.ac.uk/ott/ Outreach and Training Team] (Cath Brooksbank)
: Coordinates firstly communicating the scientific mission and activities of the EBI to the community and secondly the scientific training programme of the EBI. The EBI’s user-training programme equips users of the EBI’s bioinformatics services with the knowledge that they need to use our data resources. It includes:
; [http://www.ebi.ac.uk/training/roadshow/ The Bioinformatics Roadshow]: a travelling user-training programme that is tailored to the needs of users of Europe’s main data resources.
; [http://www.ebi.ac.uk/training/handson/ The EBI Hands-on User Training programme]: a series of short courses, held in the EBI’s IT training suite, that aims to familiarise experimental researchers with the EBI’s core data resources.--------->
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