Diferencia entre revisiones de «Instituto Europeo de Bioinformática»

Categoría Bioinformática
(Categoría Bioinformática)
'''European Bioinformatics Institute''' o '''EBI''' (Instituto Europeo de Bioinformática) es un centro de investigación en [[bioinformática]] situado en [[Hinxton]], [[Cambridge]], [[Reino Unido]]. Pertenece al [[European Molecular Biology Laboratory]] o EMBL (Laboratorio Europeo de Biología Molecular). Es pionero en investigación bioinformática, proporcionando herramientas para la comprensión de los datos [[genómica|genómicos]] y [[proteómica|proteómicos]].
El '''Instituto Europeo de Bioinformática''' ('''EBI''', por sus siglas en inglés) es una organización académica sin ánimo de lucro que forma parte del '''Laboratorio Europeo de Biología Molecular'''. El EBI es una centro dedicado a la investigación y uso de servicios [[Bioinformática|bioinformáticos]]. Administra [[base de datos|bases de datos]] que contienen secuencias de [[ácido nucleico|ácidos nucleicos]], [[proteína]]s y estructuras macromoleculares.
== Grupos ==
 
Fue fundado gracias a los fondos de los 20 estados miembros del EMBL, además de la [[Comisión Europea]], [[Wellcome Trust]], «US National Institutes of Health», «UK Research Councils», empresas del sector y el «Department of Trade and Industry» de Reino Unido.
; [http://www.ebi.ac.uk/msd/ Macromolecular Structure Database] (Kim Henrick)
: Proporciona lista de proteínas (estructura cuaternaria o [[macromolécula]]s) para cada entrada en la base de datos de proteinas (PDB; [http://www.rcsb.org/pdb/]. Es también miembro de Banco de Datos Mundial de Proteinas (Worldwide Protein Data Bank), y uno de los tres sitios en el mundo que acepta, procesa y distribuye datos sobre estructuras de macromoléculas
; [http://www.ebi.ac.uk/panda PANDA Protein And Nucleotide DAtabase group][[Ensembl]] (Rolf Apweiler & [[Ewan Birney]]))<!-----------
 
==Utilidades y bases de datos ==
: Provides, for almost 35 species, a [http://www.ensembl.org/ genome browser], public access to the [[MySQL]] databases of annotations shown in the browser, and a [[Perl]] [[API]] for accessing the database. The group is divided fairly equally between the EBI and the [[Wellcome Trust Sanger Institute]] with gene builders and web team on the Sanger side, and core database and [[comparative genomics]] teams at the EBI.
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; [http://www.ebi.ac.uk/Thornton Thornton Group] ([[Janet Thornton]])
*[http://www.ebi.ac.uk/embl Página webEMBL-Bank] (en inglés)
: Using biomolecular structures, tries to understand enzyme active sites, protein-protein interactions, protein-ligand interactions, protein-DNA interactions and structure and modelling.
; *[http://www.ebi.ac.uk/GoldmanDatabases/genomes.html Goldman GroupGenomas] (Nick Goldman)
*[http://www.ebi.ac.uk/Databases/microarray.html Expresión génica]
: Develops methods for the analysis of DNA and amino acid sequences to study evolution.
; *[http://www.ebi.ac.uk/microarrayDatabases/literature.html Microarray GroupPublicaciones] (Alvis Brazma)
*[http://www.ebi.ac.uk/Tools/similarityandanalysis.html Análisis de [[alineamiento de secuencias|secuencias]] por similitud]
: Uses microarray technology to analyse the sequence data from the genome projects to identify which genes are expressed in a particular cell type of an organism.
; *[http://www.ebiuniprot.ac.uk/Rice/org Peter Rice GroupUniProt] (Peter Rice)
*[http://www.ebi.ac.uk/Databases/nucleotide.html Secuencias de nucleótidos]
: Investigates & advises on the [[e-Science]] and [[Grid computing|Grid]] technology requirements of the EMBL-EBI, through application development plus participation in standards development. See [[MyGrid]] and [[EMBOSS]]
; *[http://www.ebi.ac.uk/compneurintact/ ComputationalInteracciones Neurobiology Groupmoleculares] (Nicolas Le Novère)
*[http://www.ebi.ac.uk/newt/ Taxonomía]
: The interests of the group Computational Neurobiology revolve around [[signal transduction]] in [[neurons]], ranging from the [[molecular structure]] of [[membrane proteins]] involved in [[neurotransmission]] to modelling signalling pathways. A strong focus is the molecular and cellular basis of [[synaptic plasticity]] in neurons of the [[basal ganglia]]. The group also provide tools and resources for [[computational systems biology]], including the [[SBO]], the Systems Biology Ontology, [[MIRIAM]] Resources, plus software to develop models. A main project of the group is the [[BioModels Database]], which allows biologists to store, search and retrieve published mathematical models of biological interest.
; *[http://www.ebi.ac.uk/RebholzTools/protein.html RebholzBúsqueda Group]de (Dietrichmotivos Rebholz-Schuhmann)y pautas estructurales]
*[http://www.ebi.ac.uk/arrayexpress/ Análisis de arrays]
: Focuses on extraction of facts from scientific literature in molecular biology. The main methods are based on Finite State Automatons (FSAs). In the past has worked on the identification of protein-protein interactions, acronyms and descriptions of mutations.
; *[http://www.ebi.ac.uk/huberDatabases/protein.html HuberAnálisis Group]de (Wolfgangsecuencias Huber)proteicas]
*[http://www.ebi.ac.uk/Databases/pathways.html Reacciones y vías]
: Focuses on gene transcription and protein-DNA binding analysis with DNA microarrays; statistical computing and high-throughput cellular assays and genetic interaction screens.
; *[http://www.ebi.ac.uk/proteomicsDatabases/geneontology.html Proteomics Services TeamOntologías] (Henning Hermjakob)
*[http://www.ebi.ac.uk/Tools/structural.html Análisis estructural]
: Provides databases and tools for the deposition, distribution and analysis of proteomics and proteomics-related data.
; *[http://www.ebiensembl.ac.uk/interpro/org InterPro GroupEnsembl] (Sarah Hunter)
*[http://www.ebi.ac.uk/Databases/structure.html Estructuras macromoleculares]
: Develops and maintains the InterPro project, an integrated documentation resource for protein families, domains and functional sites that is used for small and large-scale functional classification of proteins.
; *[http://www.ebi.ac.uk/luscombeDatabases/proteinfamilies.html RegulationFamilias Groupde proteíans] (Nick Luscombe)
*[http://www.ebi.ac.uk/Rebholz/ Text Mining]
: Focuses on the genomic analysis of regulatory systems.
; *[http://www.ebi.ac.uk/bertoneinterpro/ Bertone GroupInterPro] (Paul Bertone)
*[http://www.ebi.ac.uk/Databases/smallmolecules.html Pequeñas moléculas]
: Genomic analysis of developmental pathways, with a focus on differentiation and lineage commitment in mammalian embryonic stem cells.
*[http://www.ebi.ac.uk/Databases/enzymes.html Enzimas]
; Database Application Group (Weimin Zhu)
*[http://www.ebi.ac.uk/FTP/ Downloads]
: Consists of software engineers from the Sequence Database Group, and database professionals from the Database Support Team, which belongs to the EBI IT Service Group. It supports software and database development for new projects, and maintains support for the projects in production. It continually does research in software engineering and database technologies, to meet new requirements from users, and to find better solutions to the challenges in areas such as solid application framework, data integration and best practices.
; *[http://www.ebi.ac.uk/literaturepdbe/ Literature ServicesPDBe] (Peter Stoehr)
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: This group is in charge of the development and maintenance of [http://www.ebi.ac.uk/citexplore CitExplore] and related services.
== Proyectos hospedados ==
; Systems Group (Petteri Jokinen)
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: Maintains and develops state-of-art computing infrastructure on which most EBI operations are run.
* [http://www.1000genomes.org 1000 Genomes]
; [http://www.ebi.ac.uk/es/index.html External Services Group] (Rodrigo Lopez)
* [http://www.biocatalog.org BioCatalog]
: Develops and maintains [http://www.ebi.ac.uk/tools/webservices/ Web Services APIs] for most tools available from EMBL-EBI, The [[EB-eye_EBI's_Search_Engine]], [http://srs.ebi.ac.uk/ EBI SRS servers], [http://www.ebi.ac.uk/2can/ 2can] for external as well as internal users. See also [http://www.ebi.ac.uk/es/ EBI External Services]
* [http://www.biosapiens.info BioSapiens]
; Bioinformatics educational resource [http://www.ebi.ac.uk/2can 2can Bioinformatics]
* [http://www.ensembl.org ENSEMBL ] - junto al [[Sanger_Institute]]
: Provides short and concise introductions to basic concepts in molecular and cell biology and bioinformatics. It focuses on making it as easy for the user to understand which tools and databases are available from the EBI and collaborating sites. It also provides links to other sites where similar resources are maintained and well supported.
;* [http://www.ebi.ac.uk/otte-mep/ Outreach and Training TeamE-Mep] (Cath Brooksbank)
* [http://www.elixir-europe.org/ ELIXIR]
: Coordinates firstly communicating the scientific mission and activities of the EBI to the community and secondly the scientific training programme of the EBI. The EBI’s user-training programme equips users of the EBI’s bioinformatics services with the knowledge that they need to use our data resources. It includes:
* [http://www.embracegrid.info/ EMBRACE]
; [http://www.ebi.ac.uk/training/roadshow/ The Bioinformatics Roadshow]: a travelling user-training programme that is tailored to the needs of users of Europe’s main data resources.
* [http://www.microarray-quality.org/ EMERALD]
; [http://www.ebi.ac.uk/training/handson/ The EBI Hands-on User Training programme]: a series of short courses, held in the EBI’s IT training suite, that aims to familiarise experimental researchers with the EBI’s core data resources.--------->
* [http://www.enfin.org/ ENFIN]
* [http://www.felics.org/ FELICS]
* [http://www.insdc.org/ INSDC ]
* [http://www.symbiomatics.org/ SYMBIOmatics]
* [http://www.uniprot.org UniProt] - junto al [[Swiss_Institute_of_Bioinformatics|SIB]],
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[[enCategoría:Bioinformática|European Bioinformatics Institute]]
 
{{esbozo de |bioinformática}}
==Enlaces externos==
*[http://www.ebi.ac.uk/ Página web] (en inglés)
[[de:European Bioinformatics Institute]]
[[es:Instituto Europeo de Bioinformática]]
[[en:European Bioinformatics Institute]]
[[fr:Institut européen de bio-informatique]]
[[it:European Bioinformatics Institute]]
[[nl:European Bioinformatics Institute]]
[[ja:欧州バイオインフォマティクス研究所]]
[[en:European Bioinformatics Institute]]