Diferencia entre revisiones de «Muscimol»
Contenido eliminado Contenido añadido
Sin resumen de edición |
|||
Línea 1:
{{Ficha de compuesto químico
| nombre = Muscimol
| imagen = Muscimol chemical structure.svg
| ImageSize = 170px
| imagen2 = Muscimol3d.png
| ImageSize2 = 150px
| IUPAC = 5-(Aminomethyl)-isoxazol-3-ol
| OtherNames =
| Abbreviations =
| InChI = 1/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)
| InChIKey = ZJQHPWUVQPJPQT-UHFFFAOYAI
| ChEMBL = 273481
| StdInChI = 1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)
| StdInChIKey = ZJQHPWUVQPJPQT-UHFFFAOYSA-N
| CAS = 2763-96-4
| masa = 114.10
| EINECS =
| PubChem = 4266
| ChemSpiderID = 4116
| SMILES = O=C1/C=C(\ON1)CN
| C=4|H=6|N=2|O=2
| MeltingPtCL = 184
| MeltingPtCH = 185
| Solubility = very soluble
| Solubility1 = very soluble
| Solvent1 = methanol
| SolubleOther = slightly soluble
| Solvent = ethanol
}}
'''Muscimol''' es el componente psicoactivo alcaloide presente en muchas [[seta]]s del género ''[[Amanita]]''. No se parece a otros tipos de psicoactivos como la [[psilocibina]] o [[triptamina]]. El muscimol es un potente y selectivo agonista de los receptores GABA.
Línea 8 ⟶ 37:
{{listaref}}
* {{cite journal | doi = 10.1002/syn.890190306 | author = Ito Y, Segawa K, Fukuda H | year = 1995 | title = Functional diversity of GABAA receptor ligand-gated chloride channels in rat synaptoneurosomes | url = | journal = Synapse | volume = 19 | issue = 3| pages = 188–96 | pmid = 7784959 }}
* Rätsch, Christian. (1998). The Encyclopedia of Psychoactive Plants. Rochester, VT: Park Street Press.
*{{cite journal
| author = Beaumont K, Chilton W. S., Yamamura H. I., Enna S. J.
| title = Muscimol binding in rat brain: association with synaptic GABA receptors
| journal = [[Brain Res.]]
| year = 1978
| volume = 148
| issue = 1
| pages = 153–62
| doi = 10.1016/0006-8993(78)90385-2
| pmid=207386
}}
*{{cite journal
| author = S. R. Snodgrass
| title = Use of <sup>3</sup>H-muscimol for GABA receptor studies
| journal = [[Nature (journal)|Nature]]
| year = 1978
| volume = 273
| issue = 1
| pages = 392–394
| doi = 10.1038/273392a0
}}
*{{cite journal
| author = G. A. R. Johnston, D. R. Curtis, W. C. de Groat and A. W. Duggan
| title = Central actions of ibotenic acid and muscimol
| journal = [[Biochemical Pharmacology]]
| year = 1968
| volume = 17
| issue = 12
| pages = 2488–2489
| doi = 10.1016/0006-2952(68)90141-X
| pmid=5752907
}}
*{{cite journal |author=Tamminga CA, Neophytides A, Chase TN, Frohman LA |title=Stimulation of prolactin and growth hormone secretion by muscimol, a gamma-aminobutyric acid agonist |journal=J. Clin. Endocrinol. Metab. |volume=47 |issue=6 |pages=1348–51 |year=1978 |month=December |pmid=162520 |doi=10.1210/jcem-47-6-1348 |url=}}
[[Categoría:Alcaloides]]
[[Categoría:Enteógenos]]
| |||