Diferencia entre revisiones de «Activina e inhibina»
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== Clinical significance ==
Quantification of inhibin A is part of the prenatal [[quad screen]] that can be administered during pregnancy at a gestational age of 16-18 weeks. An elevated inhibin A (along with an increased [[beta-hCG]], decreased [[Alpha-fetoprotein|AFP]], and a decreased [[estriol]]) is<ref>
{{cita publicación |autor=Aitken D, Wallace E, Crossley J, Swanston I, van Pareren Y, van Maarle M, Groome N, Macri J, Connor J |título=Dimeric inhibin A as a marker for Down's syndrome in early pregnancy |publicación=N Engl J Med |volumen=334 |número=19 |páginas=1231-6 |año=1996 |pmid=8606718 | url = http://content.nejm.org/cgi/content/short/334/19/1231 }}</ref> suggestive of the presence of a fetus with [[Down's syndrome]]. As a screening test, abnormal quad screen test results need to be followed up with more definitive tests.
It also has been used as a marker for [[ovarian cancer]].<ref>{{cita publicación |autor=Robertson D, Pruysers E, Jobling T |título=Inhibin as a diagnostic marker for ovarian cancer |publicación=Cancer Lett |volumen= |número= |páginas= |año= |pmid=17320281}}</ref><ref>{{cita publicación |autor=Robertson D, Pruysers E, Burger H, Jobling T, McNeilage J, Healy D |título=Inhibins and ovarian cancer |publicación=Mol Cell Endocrinol |volumen=225 |número=1-2 |páginas=65-71 |año=2004 |pmid=15451569}}</ref>
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== Referencias ==
{{Listaref|2}}
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