| Imagen = [[Archivo:Streptomycin2.svg |thumb]]▼{{Ficha de medicamento
| IUPAC_name = 5-(2,4-diguanidino-<br>3,5,6-trihydroxy-cyclohexoxy)- 4-[4,5-dihydroxy-6-(hydroxymethyl)<br>-3-methylamino-tetrahydropyran-2-yl] oxy-3-hydroxy-2-methyl<br>-tetrahydrofuran-3-carbaldehyde
▲| Imagen = Streptomycin2.svg
| image2 = Streptomycin-1ntb-xtal-3D-balls.png
| Número_CAS = 57-92-1
| ChemSpiderID = 18508
| ATC_prefix = A07
| ATC_suffix = AA04
| ATC_supplemental = {{ATC|J01|GA01}}
| PubChem = 5999
| DrugBank = DB01082
| C=21 | H=39 | N=7 | O=12
| Peso_molecular = 581.574 g/mol
| smiles =
| melting_point = 12
| bioavailability = 84% to 88% (est.)<ref name="Zhu2001">
{{cite journal
| author = Zhu M, Burman WJ, Jaresko GS, Berning SE, Jelliffe RW, Peloquin CA.
| date = September 2001
| title = Population pharmacokinetics of intravenous and intramuscular streptomycin in patients with tuberculosis
| journal = [[Pharmacotherapy (journal)|Pharmacotherapy]]
| volume = 21
| issue = 9
| pages = 1037–1045
| pmid = 11560193
| doi = 10.1592/phco.21.13.1037.34625
| url = http://www.medscape.com/viewarticle/409778
| accessdate = 2010-05-25
}}
</ref>
| metabolism =
| elimination_half-life = 5 to 6 hours
| excretion = [[Kidney|Renal]]
| pregnancy_category = DM<ref name="dsafepreg">
{{cite web
| url = http://drugsafetysite.com/streptomycin
| author =
| date = 2006
| title = Taking Streptomycin during pregnancy and breastfeeding
| accessdate = 2010-05-25
| publisher = Drug Safety Site
}}
</ref>
| routes_of_administration = [[Intramuscular injection|Intramuscular]], [[Intravenous therapy|intravenous]]
| legal_US = Rx-only
| legal_UK = POM
| width = 208}}
'''Streptomycin''' is an [[antibiotic]] drug, the first of a class of drugs called [[aminoglycoside]]s to be discovered, and was the first antibiotic remedy for [[tuberculosis]]. It is derived from the [[actinobacteria|actinobacterium]] ''[[Streptomyces griseus]]''. Streptomycin is a bactericidal antibiotic<ref name="Singh1954">
{{cite journal
| author = Singh B, Mitchison DA
| date = 16 January 1954
| title = Bactericidal activity of streptomycin and isoniazid against tubercle bacilli
| journal = [[British Medical Journal]]
| volume = 1
| issue = 4854
| pages = 130–132
| pmc = 2084433
| pmid = 13106497
| doi = 10.1136/bmj.1.4854.130
}}
</ref>. Streptomycin cannot be given orally, but must be administered by regular [[intramuscular injection]]s. An adverse effect of this medicine is [[ototoxicity]], which can lead to hearing loss{{Citation needed|date=May 2010}}.
La '''estreptomicina''' fue el primer [[antibiótico]] descubierto del grupo de los [[aminoglucósido]]s; también fue el primer [[fármaco]] de la era de la [[quimioterapia]] usado en el [[tratamiento]] de la [[tuberculosis]]. Es un antibiótico bactericida de espectro pequeño, derivado de la [[actinobacteria]] ''Streptomyces griseus''.
| 