Receptor testicular 2

Receptor testicular 2
Estructuras disponibles
PDB	Buscar ortólogos: PDBe, RCSB
Identificadores
Símbolos	NR2C1 (HGNC: 7971) TR2, TR2-11
Identificadores; externos	OMIM: 601529 ; EBI: NR2C1; GeneCards: Gen NR2C1; UniProt: NR2C1;
Locus	Cr. 12 q22
	Referencias: AmiGO / QuickGO
Ortólogos
Humano	Ratón
7181
P13056	n/a
NP_001027458	n/a
	v; t; e;
	[editar datos en Wikidata]

El receptor testicular 2 (TR2) es un factor de transcripción perteneciente a la familia de los receptores nucleares, codificado en humanos por el gen HGNC NR2C1 (de sus siglas en inglés "nuclear receptor subfamily 2, group C, member 1").^[1]

Interacciones editar

El receptor testicular 2 ha demostrado ser capaz de interaccionar con:

↑ «Entrez Gene: NR2C1 nuclear receptor subfamily 2, group C, member 1».
↑ Hu, Yueh-Chiang; Shyr Chih-Rong, Che Wenyi, Mu Xiao-Min, Kim Eungseok, Chang Chawnshang (Sep. de 2002). «Suppression of estrogen receptor-mediated transcription and cell growth by interaction with TR2 orphan receptor». J. Biol. Chem. (United States) 277 (37): 33571-9. ISSN 0021-9258. PMID 12093804. doi:10.1074/jbc.M203531200.
↑ Li, Guangjin; Franco Peter J, Wei Li-Na (Oct. de 2003). «Identification of histone deacetylase-3 domains that interact with the orphan nuclear receptor TR2». Biochem. Biophys. Res. Commun. (United States) 310 (2): 384-90. ISSN 0006-291X. PMID 14521922.
↑ ^a ^b Franco, Peter J; Li Guangjin, Wei Li-Na (Aug. de 2003). «Interaction of nuclear receptor zinc finger DNA binding domains with histone deacetylase». Mol. Cell. Endocrinol. (Ireland) 206 (1-2): 1-12. ISSN 0303-7207. PMID 12943985.
↑ ^a ^b Franco, P J; Farooqui M, Seto E, Wei L N (Aug. de 2001). «The orphan nuclear receptor TR2 interacts directly with both class I and class II histone deacetylases». Mol. Endocrinol. (United States) 15 (8): 1318-28. ISSN 0888-8809. PMID 11463856.
↑ Mu, Xiaomin; Chang Chawnshang (Oct. de 2003). «TR2 orphan receptor functions as negative modulator for androgen receptor in prostate cancer cells PC-3». Prostate (United States) 57 (2): 129-33. ISSN 0270-4137. PMID 12949936. doi:10.1002/pros.10282.