GTF2F1

Subunidad 1 del factor iniciador de la transcripción IIF
	; Estructura tridimensional de la proteína GTF2F1.
Estructuras disponibles
PDB	Buscar ortólogos: PDBe, RCSB Lista de códigos PDB 1f3u
Identificadores
Símbolos	GTF2F1 (HGNC: 4652) BTF4; RAP74; TF2F1; TFIIF
Identificadores; externos	OMIM: 189968 ; EBI: GTF2F1; GeneCards: Gen GTF2F1; UniProt: GTF2F1;
Locus	Cr. 19 p13.3
	Referencias: AmiGO / QuickGO
Ortólogos
Humano	Ratón
2962
P35269	n/a
NP_002087	n/a
	v; t; e;
	[editar datos en Wikidata]

La subunidad 1 del factor iniciador de la transcripción IIA (GTF2A1) es una proteína codificada en humanos por el gen gtf2A1.^[1]^[2]

Interacciones

La proteína GTF2F1 ha demostrado ser capaz de interaccionar con:

Véase también

Factor de transcripción II F

Referencias

↑ DeJong J, Roeder RG (Dec de 1993). «A single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIA». Genes Dev 7 (11): 2220-34. PMID 8224848.
↑ «Entrez Gene: GTF2A1 general transcription factor IIA, 1, 19/37kDa».
↑ Dikstein, R; Ruppert S; Tjian R (Mar. de 1996). «TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74». Cell (UNITED STATES) 84 (5): 781-90. ISSN 0092-8674. PMID 8625415.
↑ ^a ^b Ruppert, S; Tjian R (Nov. de 1995). «Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation». Genes Dev. (UNITED STATES) 9 (22): 2747-55. ISSN 0890-9369. PMID 7590250.
↑ Siegert, J L; Robbins P D (Jan. de 1999). «Rb inhibits the intrinsic kinase activity of TATA-binding protein-associated factor TAFII250». Mol. Cell. Biol. (UNITED STATES) 19 (1): 846-54. ISSN 0270-7306. PMID 9858607.
↑ ^a ^b Malik, S; Guermah M, Roeder R G (Mar. de 1998). «A dynamic model for PC4 coactivator function in RNA polymerase II transcription». Proc. Natl. Acad. Sci. U.S.A. (UNITED STATES) 95 (5): 2192-7. ISSN 0027-8424. PMID 9482861.
↑ Kim, M K; Nikodem V M (Oct. de 1999). «hnRNP U inhibits carboxy-terminal domain phosphorylation by TFIIH and represses RNA polymerase II elongation». Mol. Cell. Biol. (UNITED STATES) 19 (10): 6833-44. ISSN 0270-7306. PMID 10490622.
↑ ^a ^b ^c ^d ^e ^f Scully, R; Anderson S F, Chao D M, Wei W, Ye L, Young R A, Livingston D M, Parvin J D (mayo. de 1997). «BRCA1 is a component of the RNA polymerase II holoenzyme». Proc. Natl. Acad. Sci. U.S.A. (UNITED STATES) 94 (11): 5605-10. ISSN 0027-8424. PMID 9159119.
↑ Archambault, J; Pan G, Dahmus G K, Cartier M, Marshall N, Zhang S, Dahmus M E, Greenblatt J (Oct. de 1998). «FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO». J. Biol. Chem. (UNITED STATES) 273 (42): 27593-601. ISSN 0021-9258. PMID 9765293.
↑ Cho, H; Orphanides G, Sun X, Yang X J, Ogryzko V, Lees E, Nakatani Y, Reinberg D (Sep. de 1998). «A human RNA polymerase II complex containing factors that modify chromatin structure». Mol. Cell. Biol. (UNITED STATES) 18 (9): 5355-63. ISSN 0270-7306. PMID 9710619.
↑ Suñé, C; Hayashi T, Liu Y, Lane W S, Young R A, Garcia-Blanco M A (Oct. de 1997). «CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription». Mol. Cell. Biol. (UNITED STATES) 17 (10): 6029-39. ISSN 0270-7306. PMID 9315662.
↑ Joliot, V; Demma M; Prywes R (Feb. de 1995). «Interaction with RAP74 subunit of TFIIF is required for transcriptional activation by serum response factor». Nature (ENGLAND) 373 (6515): 632-5. ISSN 0028-0836. PMID 7854423. doi:10.1038/373632a0.
↑ Zhu, H; Joliot V; Prywes R (Feb. de 1994). «Role of transcription factor TFIIF in serum response factor-activated transcription». J. Biol. Chem. (UNITED STATES) 269 (5): 3489-97. ISSN 0021-9258. PMID 8106390.
↑ Fang, S M; Burton Z F (mayo. de 1996). «RNA polymerase II-associated protein (RAP) 74 binds transcription factor (TF) IIB and blocks TFIIB-RAP30 binding». J. Biol. Chem. (UNITED STATES) 271 (20): 11703-9. ISSN 0021-9258. PMID 8662660.

Enlaces externos

MeSH: GTF2F1+protein,+human (en inglés)

Datos: Q369310

[pmid8224848-1] DeJong J, Roeder RG (Dec de 1993). «A single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIA». Genes Dev 7 (11): 2220-34. PMID 8224848.

[entrez-2] «Entrez Gene: GTF2A1 general transcription factor IIA, 1, 19/37kDa».

[pmid8625415-3] Dikstein, R; Ruppert S; Tjian R (Mar. de 1996). «TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74». Cell (UNITED STATES) 84 (5): 781-90. ISSN 0092-8674. PMID 8625415.

[pmid7590250-4] Ruppert, S; Tjian R (Nov. de 1995). «Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation». Genes Dev. (UNITED STATES) 9 (22): 2747-55. ISSN 0890-9369. PMID 7590250.

[pmid9858607-5] Siegert, J L; Robbins P D (Jan. de 1999). «Rb inhibits the intrinsic kinase activity of TATA-binding protein-associated factor TAFII250». Mol. Cell. Biol. (UNITED STATES) 19 (1): 846-54. ISSN 0270-7306. PMID 9858607.

[pmid9482861-6] Malik, S; Guermah M, Roeder R G (Mar. de 1998). «A dynamic model for PC4 coactivator function in RNA polymerase II transcription». Proc. Natl. Acad. Sci. U.S.A. (UNITED STATES) 95 (5): 2192-7. ISSN 0027-8424. PMID 9482861.

[pmid10490622-7] Kim, M K; Nikodem V M (Oct. de 1999). «hnRNP U inhibits carboxy-terminal domain phosphorylation by TFIIH and represses RNA polymerase II elongation». Mol. Cell. Biol. (UNITED STATES) 19 (10): 6833-44. ISSN 0270-7306. PMID 10490622.

[pmid9159119-8] ↑ ^a ^b ^c ^d ^e ^f Scully, R; Anderson S F, Chao D M, Wei W, Ye L, Young R A, Livingston D M, Parvin J D (mayo. de 1997). «BRCA1 is a component of the RNA polymerase II holoenzyme». Proc. Natl. Acad. Sci. U.S.A. (UNITED STATES) 94 (11): 5605-10. ISSN 0027-8424. PMID 9159119.

[pmid9765293-9] Archambault, J; Pan G, Dahmus G K, Cartier M, Marshall N, Zhang S, Dahmus M E, Greenblatt J (Oct. de 1998). «FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO». J. Biol. Chem. (UNITED STATES) 273 (42): 27593-601. ISSN 0021-9258. PMID 9765293.

[pmid9710619-10] Cho, H; Orphanides G, Sun X, Yang X J, Ogryzko V, Lees E, Nakatani Y, Reinberg D (Sep. de 1998). «A human RNA polymerase II complex containing factors that modify chromatin structure». Mol. Cell. Biol. (UNITED STATES) 18 (9): 5355-63. ISSN 0270-7306. PMID 9710619.

[pmid9315662-11] Suñé, C; Hayashi T, Liu Y, Lane W S, Young R A, Garcia-Blanco M A (Oct. de 1997). «CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription». Mol. Cell. Biol. (UNITED STATES) 17 (10): 6029-39. ISSN 0270-7306. PMID 9315662.

[pmid7854423-12] Joliot, V; Demma M; Prywes R (Feb. de 1995). «Interaction with RAP74 subunit of TFIIF is required for transcriptional activation by serum response factor». Nature (ENGLAND) 373 (6515): 632-5. ISSN 0028-0836. PMID 7854423. doi:10.1038/373632a0.

[pmid8106390-13] Zhu, H; Joliot V; Prywes R (Feb. de 1994). «Role of transcription factor TFIIF in serum response factor-activated transcription». J. Biol. Chem. (UNITED STATES) 269 (5): 3489-97. ISSN 0021-9258. PMID 8106390.

[pmid8662660-14] Fang, S M; Burton Z F (mayo. de 1996). «RNA polymerase II-associated protein (RAP) 74 binds transcription factor (TF) IIB and blocks TFIIB-RAP30 binding». J. Biol. Chem. (UNITED STATES) 271 (20): 11703-9. ISSN 0021-9258. PMID 8662660.

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