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Scrapie is infectious and transmissible among conspecifics, so one of the most common ways to contain it (since it is incurable) is to quarantine and destroy those affected. However, scrapie tends to persist in flocks and can also arise apparently spontaneously in flocks that have not previously had cases of the disease. The mechanism of transmission between animals and other aspects of the biology of the disease are only poorly understood, and these are active areas of research. Recent studies suggest [[prion]]s may be spread through urine and persist in the environment for decades.<ref name="pmid12793776">{{cite journal
|author=Detwiler LA, Baylis M
|title=The epidemiology of scrapie
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